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The Treatment Resistance Team, led by Prof Gerhardt Attard, focuses on identifying and overcoming treatment resistance in prostate cancer. The group has been integrating liquid and solid biopsy multiomic analysis to discover novel markers for patient stratification and to track tumour clone dynamics in patients progressing through multiple lines of treatment. The overall aims are to improve the management and detection of prostate cancer patients and to discover novel drivers of resistance in multiple cancer types.
You will hold a PhD, or be close to completing one, in a relevant biological or biomedical discipline, with substantial hands-on experience in next-generation sequencing workflows, including whole genome library generation, targeted sequencing and sequencing data analysis. You will have experience of nucleic acid extraction, managing research samples and databases, and working with genomic datasets using programming languages such as R and/or Python. Knowledge of prostate cancer biology and familiarity with GCP and HTA requirements are also essential.
You will be a highly organised and motivated researcher, capable of working independently while also contributing effectively as part of a collaborative research team. You will be comfortable managing multiple projects simultaneously, maintaining accurate records, and communicating scientific findings clearly through both written reports and presentations.
We are looking for a candidate who is committed to high-quality research, excellent research practice and UCL's values. Experience of long-read sequencing and single-cell sequencing workflows would be advantageous, as would a willingness to contribute to the wider life of the department and institution.
Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B, with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.
Applications should include a CV and a Cover Letter: In the Cover Letter please provide evidence of the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.)
The role will be available for 18 months in the first instance with the possibility of extension.
The UCL Cancer Institute is the hub for basic biological and translational cancer research at University College London, one of the world's leading universities. The Institute draws together over 400 talented scientists who are working together to translate research discoveries into developing more effective therapies for cancer patients. The UCL Cancer Institute is part of the CRUK City of London Centre, which draws together the expertise present in four leading centres for cancer research, UCL, Barts, KCL and the Francis Crick Institute.
Further Information about the UCL Cancer Institute can be found on our website https://www.ucl.ac.uk/cancer/
For rewards and benefits at UCL please visit:
Staff Benefits | UCL People & Culture - UCL - University College London
As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.
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