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CRA II/Senior CRA - Early Phase

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

As a CRA II or Senior CRA within our Early Phase team, you'll play a critical role in studies that sit at the very beginning of the drug development journey, including first-in-human and proof-of-concept research. Working alongside leading investigators, sponsors, and specialist clinical teams, you'll help advance promising new therapies from concept to clinical reality.

Unlike traditional large-scale monitoring roles, you'll focus on a smaller portfolio of approximately 3-4 sites across the UK, enabling you to build strong site relationships, maintain exceptional quality oversight, and make a genuine impact on the success of each study.

What You'll Be Doing

• Managing site qualification, initiation, monitoring and close-out activities across a portfolio of UK Early Phase studies.
• Building strong partnerships with investigators and site teams to ensure study success.
• Ensuring patient safety, protocol compliance, and data integrity throughout the clinical trial lifecycle.
• Reviewing study data, resolving site queries, and proactively identifying and mitigating risks.
• Supporting sponsors and project teams through the unique operational challenges associated with early development programmes.
• Acting as a trusted clinical research expert, providing guidance and support to sites and internal stakeholders.

What We're Looking For

• CRA II: Previous independent monitoring experience across clinical trials.
• Senior CRA: Significant independent monitoring experience with the ability to manage complex studies and act as a mentor for less experienced colleagues.
• Strong understanding of ICH-GCP, regulatory requirements, and clinical trial operations.
• Excellent relationship-building and communication skills.
• Ability to work proactively, independently, and collaboratively within a global study team.
• Life Science, Nursing, Pharmacy, or other relevant healthcare degree (or equivalent experience).
• Able to travel across the UK as required to complete onsite visits

What ICON can offer you:
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

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At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply